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Oian, J. Combinationdrug therapy of seropositive rheumatoid arthritis.


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Wilke, J. Therapy for rheumatoid arthritis: combinationsof disease-modifying drugs and new paradigms of treatment. Semin Arthritis Rheum, 21 , pp.

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Langevitz, N. Kaplinsky, M. Ehrenfeld, M. Pras, R. A Intractable. Br J Rheumatol, 28 , pp. Scott, P. Dawes, E. Tunn, P. Fowler, M. Shandforth, J. Fisher, et al. Combination therapy with gold and hydroxychloroquine in rheumatoidarthritis: a prospective, randomized, placebo-controlled study. Porter, H. Capell, J.

Combination therapy in rheumatoidarthritis—no benefit of addition of hydroxychloroquine to patients with asuboptimal response to intramuscular gold therapy. A combination of D-penicillamine and hydroxychloroquine for the treatment of rheumatoid arthritis. Ann Rheum Dis, 41 , pp. Bunch, J. Tompkin, W. Controlled trial of hydroxychloroquine and D-penicillamine singly and in combination in the treatment of rheumatoid arthritis. Arthritis Rheum, 27 , pp. Gibson, P. Emery, R. Armstrong, A. Crisp, G. Combined D-penicillamine and chloroquine treatment of rheumatoid arthritis-a comparative study.

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Hydroxychloroquine and sulphasalazine alone and in combination in rheumatoid arthritis: a randomised double blind trial. Rheum Dis, 52 , pp. Fries, G. Singh, L. Lenert, D. Aspirin, hydroxychloroquine, and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis.

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Arthritis Rheum, 33 , pp. Seideman, F. Albertioni, O. Beck, S. Eksborg, C. Chloroquinereduces the bioavailability of methotrexate in patients with rheumatoidarthritis.

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A possible mechanism of reduced hepatotoxicity. Arthritis Rheum, 37 , pp. Haire, N. Erikson, W. Drymalski, W.

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Palmer, S. Eckiioff, et al. Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications.?. Engl J Med, , pp. Mottonen, P. Hannonen, M. Leirisalo-Repo, M. Nissila, H. Kautiainen, M. Korpela, et al. Comparison of combination therapy with single-drugtherapy in early rheumatoid arthritis: a randomised trial. Lancet, , pp. Calguneri, S. Pay, Z. Caliskaner, S. Apras, Kiraz, I. Combination therapy versus monotherapy for the treatment of patients with rheumatoid arthritis.

Clin Exp Rheumatol, 17 , pp. Puolakka, H. Kautiainen, T. Korpela, H. Julkunen, et al. Impact of initial aggressive drug treatment with a combinationof disease-modifying antirheumatic drugs on the development of work disability in early rheumatoid arthritis: a five-year randomized followup trial. Arthritis Rheum, 50 , pp. The use of chloroquine and hydroxychloroquine for non-infectious conditions other than rheumatoid arthritis or lupus: a critical review. SS64 Medline. Fox, E. Chan, L. Benton, M.


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